Possible Side Effects

Gastrointestinal symptoms — nausea, vomiting, diarrhea, and constipation — are by far the most common side effects of weight loss injections. The dosage and frequency of Semaglutide and Tirzepatide can influence the likelihood and severity of gastrointestinal side effects. Higher doses or rapid changes in doses, as well as improper administration or failure to adhere to dosing instructions, may increase the risk of experiencing adverse digestive reactions.

More common, less severe side effects can include:

• nausea

• vomiting

• diarrhea

• constipation

• bloating

• heartburn/acid reflux

Less common, more severe side effects can include:

• Pancreatitis: an inflammation of the pancreas that causes abdominal pain

• Gastroparesis, in which movement of food out of the stomach is slowed or stopped

• Bowel obstruction, a blockage that keeps food from passing through the intestines

• Gallstone attacks and bile duct blockage

“Ozempic Face”

Another side effect of common weight loss medications, like Semaglutide and Tirzepatide, is a term called “Ozempic Face”. This term is referred to symptoms of rapid weight loss from any GLP-1 injection. When weight is lost more gradually, these changes are more minimal and not as noticeable. Signs of rapid weight loss in the face include:

• a hollowed look to the face

• changes in the size of the lips, cheeks, and chin

• wrinkles on the face

• sunken eyes

• sagging jowls around the jaw and neck

Ways to Reduce Side Effects

To reduce side effects of Semaglutide and Tirzepatide, it’s important to follow a few guidelines:

1. Stay Hydrated: Drink plenty of water to help manage side effects like nausea, vomiting, and diarrhea.

2. Eat Smaller Meals: Eating smaller, more frequent meals can help reduce gastrointestinal side effects like nausea and vomiting.

3. Monitor Blood Sugar Levels: If you’re diabetic, closely monitor your blood sugar levels as these medications can affect glucose metabolism.

4. Follow a Balanced Diet and Exercise: Incorporate a balanced diet and regular exercise into your routine as part of the overall treatment plan.

5. Adding Vitamin B6 to the Injection: Core Aesthetic offers Semaglutide & Tirzepatide injections with Vitamin B6 to combat unwanted GI side effects & enhance overall benefits.

To help avoid gastrointestinal side effects, you should eat slowly and stop when full, have smaller portions, & avoid being too active after eating.l It is essential for individuals undergoing weight loss treatment to follow prescribed guidelines closely to minimize the risk of side effects. If you are experiencing severe vomiting or diarrhea, severe pain/tenderness in the belly, inability to pass gas or move your bowels, or jaundice, seek medical attention immediately.