Feeling bloated while on a GLP-1 medication is a common side effect for some people due to how the medication works. GLP-1s slow down gastric emptying, which means food stays in your stomach longer—helping you feel full, but also potentially causing bloating or discomfort. Additionally, smaller meal sizes, changes in digestion, and altered gut motility can contribute to that “puffed-up” feeling. Staying hydrated, eating slowly, and avoiding gas-producing foods can help manage bloating as your body adjusts to the medication.

It's common to feel a dip in energy while on a GLP-1 medication, especially in the beginning. These medications can suppress appetite so effectively that some people don’t eat enough to fuel their bodies properly—leading to fatigue, weakness, or reduced motivation to work out. Additionally, changes in blood sugar levels and mild nausea can make movement feel less appealing. Prioritizing balanced meals, staying hydrated, and starting with gentle exercise can help your body adjust and bring your energy back up.