While on a GLP-1 medication, your metabolism can shift in several ways. These medications mimic a natural hormone that helps regulate blood sugar and appetite, leading to reduced hunger, slower gastric emptying, and lower calorie intake. As you lose weight, your resting metabolic rate may also decrease slightly—this is a normal response as your body adjusts to a smaller size and lower energy needs. However, GLP-1s help counteract some of the usual metabolic slowdowns by supporting better insulin sensitivity and glycemic control. To keep your metabolism strong while on a GLP-1, it's important to maintain lean muscle through strength training, stay hydrated, eat enough protein, and stay consistent with your movement throughout the day.

Berberine is a natural compound found in several plants, including goldenseal and barberry, and has been used for centuries in traditional medicine. It’s best known for its ability to help regulate blood sugar levels, making it a popular supplement for those managing type 2 diabetes or insulin resistance. Berberine also supports cardiovascular health by improving cholesterol levels and reducing inflammation. Recent studies suggest it may aid in weight management by activating AMPK, a cellular enzyme involved in energy balance. While it offers many benefits, berberine should be taken with guidance, especially if you're on other medications, as it can interact with certain drugs.

GLP-1 medications like tirzepatide (Mounjaro, Zepbound) and semaglutide (Ozempic, Wegovy) have transformed the way many people approach weight loss. With powerful appetite regulation, improved insulin response, and steady fat loss, it can feel like a dream come true — until the weight loss slows down, or worse, stalls completely.

GLP1 agonists target GLP1 which is an incretin hormone that helps lower blood sugar by

triggering insulin. This in turns slows down how quickly the stomach empties, making you

feel fuller longer – ultimately decreasing appetite leading to weight loss.

Tirzepatide (Mounjaro or Zepbound) has been a game-changer for many people on their weight loss journey. But what happens after the injections stop? Can you keep the weight off for good?